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Other risk factors for gallstones include: having been pregnant having a family history of gallstones having recently lost lots of weight taking oral contraceptives being sedentary undergoing high-dose estrogen therapy having a gene variant that significantly increasesthe risk of developing gallstones having a high intake of dietary fat being over 60 years of age having Native American heritage taking cholesterol-lowering drugs called statins having diabetes More women get gallstones than men

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Should a patient then seek surgery, minimally invasive or open spine

Nitric oxide (NO) modulation

As we age, collagen production slows down

10.1038/s41467-021-25837-4 Nat